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MEDICATIONS




Trileptal (Oxcarbazepine)



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Trileptal is an antiepileptic drug used for treating partial-onset seizures in adults and children older than age 4. It is approved for single drug use and in combination with other antiepileptic drugs.

Dosage forms



Trileptal is available in tablets of 150 mg, 300 mg and 650 mg. It is also available as a suspension (300 mg/5ml).

What side effects can be caused by Trileptal?



Just like other drugs, Trileptal can cause side effects. Also, every patient is different. If you experience any bothersome side effects, report them to your doctor. (There is a risk of serious side effects, including death, with all medications that are used to treat seizures; however, the risk is exceedingly small). This list is not meant to be exhaustive. Please refer to the package insert for more details about Trileptal.

Some of the common side effects of Trileptal include:

  1. Lowering of the sodium level in your blood (on blood tests, also known as "hyponatremia")
  2. Sleepiness/drowsiness
  3. Coordination difficulties
  4. Difficulty concentrating
  5. Rash, especially in individuals with prior allergic reaction to Tegretol/Carbatrol (carbamazepine)
  6. Women who plan to have children should consult with their doctor about the possible effects on the fetus.

How should I take Trileptal?



It is important that you take the total dose of Trileptal as prescribed by your doctor. Trileptal is normally taken two times a day. A convenient dosing would be in the morning and at bedtime. Do not stop this medication without the advice of your doctor; doing so may result in an increase in seizures.

Does Trileptal interact with other medications?



Tegretol/Carbatrol (carbamazepine), Dilantin (phenytoin), phenobarbital and Depakote/Depakene (valproic acid) can affect levels of oxcarbazepine in the bloodstream. Trileptal can decrease the effectiveness of oral hormonal contraceptives (birth control pills).

This list is not meant to be complete. Please ask your doctor about any specific drug-drug interactions, especially when starting a new prescribed or over-the-counter drug.

Can I take Trileptal with food or other medications?



Yes, Trileptal can be taken with meals and at the same time as other medications.

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Department of Neurology | Columbia University Medical Center | Last updated: June 8, 2010 | COMMENTS? Email the administrator