Purpose: A research study to find out if the investigational drug rufinamide can help to control seizure activity.
Inclusion criteria: Age 12-80; Has refractory partial-onset seizures
Subjects will keep a seizure diary and have phone interviews for an 8 week baseline phase. Subjects are then randomized to either rufinamide or a placebo which they take for about 14 weeks. There are 7 study appointments which include a physical exam and having blood drawn. Phone visits will be conducted between office visits.